Methionine adenosyltransferase 2A regulates mouse zygotic genome activation and morula to blastocyst transition

H Sun, J Kang, J Su, J Zhang, L Zhang… - Biology of …, 2019 - academic.oup.com
… during bovine pre-implantation is closely related to methionine metabolism [6]. However,
whether methionine has the same function … the genomic regions of MAT2A associated in bovine

[HTML][HTML] Interspecific variation in one-carbon metabolism within the ovarian follicle, oocyte, and preimplantation embryo: consequences for epigenetic programming of …

CE Clare, V Pestinger, WY Kwong, DAR Tutt… - International Journal of …, 2021 - mdpi.com
… We tested the sensitivity of bovine GCs to reduced methionine (from 50 to 10 µM… It was not
our purpose to establish the full extent of errors in … MAT2A methionine adenosyltransferase 2A

CBS and MAT2A improve methionine‐mediated DNA synthesis through SAMTOR/mTORC1/S6K1/CAD pathway during embryo implantation

S Cai, Q Ye, X Zeng, G Yang, C Ye, M Chen… - Cell …, 2021 - Wiley Online Library
… between CBS and methionine adenosyltransferase 2A (MAT2A), … bovine embryos indicated
that the metabolite of methionine, S-… a critical role of CBS in improving methionine-mediated …

Ddit3 regulates key enzymes in the methionine cycle and flux during embryonic development

S Cai, S Quan, G Yang, X Zeng, X Wang, C Ye… - The Journal of …, 2023 - Elsevier
… (CBS) and methionine adenosyltransferase 2A (MAT2A), which … Gibco, USA) with 10% fetal
bovine serum, while pTr cells were … critical roles of MAT2A and CBS during fetal development

Methionine adenosyltransferase 2β participates in mouse oocyte maturation by regulating the MAPK pathway

Q An, H Sun, J Zhang, Z Lu, W Peng, S Xu… - Reproductive …, 2020 - Springer
methionine adenosyltransferase (MAT). Recent studies have reported that MAT2B also serves
specific biological functions, … 2A, Mat2b is highly expressed in the GV and MII stages. The …

Embryonic MTHFR contributes to blastocyst development

H Ishitani, S Ikeda, K Egashira, M Sugimoto… - Journal of Assisted …, 2020 - Springer
roles of MTHFR in bovine preimplantation development. … cyclic pathway that is linked to
methionine (Met) synthesis from … 2A), we cannot exclude the possibility that folate cycle is of …

Maternal nutrition, one-carbon metabolites, and programming of fetal development during early gestation

MSP Crouse - 2019 - library.ndsu.edu
… in beef heifers alters the transcript abundance of genes impacting tissue accretion, function,
… me to the field of developmental programming, a research focal area that will forever be my …

[HTML][HTML] Amino acids and the early mammalian embryo: Origin, fate, function and life-long legacy

HJ Leese, PJ McKeegan, RG Sturmey - International Journal of …, 2021 - mdpi.com
… the preimplantation stages of development and associated … of genomic regions present in
in vivo-derived bovine embryos … enzyme Methionine adenosyl transferase 2A, which converts …

[HTML][HTML] Epigenetic modifier supplementation improves mitochondrial respiration and growth rates and alters DNA methylation of bovine embryonic fibroblast cells …

MS Crouse, JS Caton, KJ Claycombe-Larson… - Frontiers in …, 2022 - frontiersin.org
… for early embryonic development due to their roles as methyl donors … Methionine
adenosyltransferase 2A is responsible for … of genes in pathways associated with growth. …

[HTML][HTML] Multifaceted role of one-carbon metabolism on immunometabolic control and growth during pregnancy, lactation and the neonatal period in dairy cattle

DN Coleman, AS Alharthi, Y Liang, MG Lopes… - Journal of Animal …, 2021 - Springer
… fertile area of research, hence, underscoring the importance for … Methionine
adenosyltransferase (MAT) converts Met to S-… their related pathways in feed-restricted, …